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In addition, many previous studies were based on relatively small number of cases on congenital anomalies and with adjustment for a limited number of potential confounders

Public health advocates worry that e-cigarettes are contributing to a new generation hooked on nicotine, a gateway to cigarette smoking that could reverse years of declining cigarette sales

Now e-cigarettes are appealing to those same aspirations. The FDA is considering expanding regulations to the e-cigarette industry, including how products are advertised

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Accessibility was evaluated by the estimated travel time to return points, which is a common proxy in consumer behavior research [77,78]